Muscle mass measures and incident osteoporosis in a large cohort of postmenopausal women.

ABSTRACT:

Background

Despite several muscle mass measures being used in the current definitions of sarcopenia, their usefulness is uncertain because of limited data on their association with health outcomes. The aim of the study was to compare the performance of different muscle mass measures for predicting incident osteoporosis in postmenopausal women.

Methods

This study included data from 149 166 participants (aged 60.3 ± 5.5 years) as part of the UK Biobank cohort. Body composition was assessed using bioelectrical impedance. The muscle mass measures included were total body skeletal muscle mass (SMM) and appendicular SMM (aSMM) divided by height squared (ht² ), derived residuals, SMM, SMM adjusted for body mass (SMM/bm × 100), and aSMM normalized for body mass index (aSM

SUBMITTER: Papageorgiou M 

PROVIDER: S-EPMC6438341 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature