NOJAH: NOt Just Another Heatmap for genome-wide cluster analysis.

ABSTRACT: Since their inception, several tools have been developed for cluster analysis and heatmap construction. The application of such tools to the number and types of genome-wide data available from next generation sequencing (NGS) technologies requires the adaptation of statistical concepts, such as in defining a most variable gene set, and more intricate cluster analyses method to address multiple omic data types. Additionally, the growing number of publicly available datasets has created the desire to estimate the statistical significance of a gene signature derived from one dataset to similarly group samples based on another dataset. The currently available number of tools and their combined use for generating heatmaps, along with the several adaptations of statistical concepts for addressin

SUBMITTER: Rupji M 

PROVIDER: S-EPMC6438523 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature