HIV Apheresis Tags (HIVAT) Aided Elimination of Viremia.

ABSTRACT:

Introduction

HIV viremia is the essential element for progression of an initial HIV infection into AIDS and death. The currently approved management relies primarily on chemotherapy repressing the HIV replication in the infected CD4+ cells, although with severe systemic adverse effects. The problem is that it does not physically eliminate viruses, which then not only keep infecting healthy cells of these patients, but also promote infections of other people.

Specific aim

An overall objective of our work is biomolecular engineering of virus apheresis tags (VAT) that eliminate viremias without adverse effects. The specific aim of this project was biomolecular engineering of Human Immunodeficiency Virus Apheresis Tags (HIVAT): CD4-Au-Fe₃O₄, CD4-SiO_2</

SUBMITTER: Malecki M 

PROVIDER: S-EPMC6438618 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature