Fat Grafting into Younger Recipients Improves Volume Retention in an Animal Model.

ABSTRACT:

Background

Soft-tissue deficits associated with various craniofacial anomalies can be addressed by fat grafting, although outcomes remain unpredictable. Furthermore, consensus does not exist for timing of these procedures. Whereas some advocate approaching soft-tissue reconstruction after the underlying skeletal foundation has been corrected, other studies have suggested that earlier grafting may exploit a younger recipient niche that is more conducive to fat graft survival. As there is a dearth of research investigating effects of recipient age on fat graft volume retention, this study compared the effectiveness of fat grafting in younger versus older animals through a longitudinal, in vivo analysis.

Methods

Human lipoaspirate from three healthy female donors was grafted su

SUBMITTER: Chung NN 

PROVIDER: S-EPMC6438719 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature