Mother's age at delivery and daughters' risk of preeclampsia.

ABSTRACT:

Background

Some cardiovascular disease risk factors are associated with both risk of preeclampsia and having been born to a younger or older mother. We examined whether mother's age at delivery predicts a primiparous daughter's risk of preeclampsia.

Methods

The analysis included 39 803 Sister Study participants (designated as "daughters") born between 1930 and 1974. Using log-binomial regression, we estimated relative risks (RR) of preeclampsia in the first pregnancy ending in birth ("primiparous preeclampsia") associated with mother's age at the daughter's birth. Models included: number of older full and maternal half-siblings, income level growing up, daughter's age at delivery, race/ethnicity, and 5-year birth cohort. We examined self-reported relative weight at age 10 (h

SUBMITTER: Basso O 

PROVIDER: S-EPMC6438740 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature