Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling.

ABSTRACT: Global surveillance of antimicrobial resistance (AMR) is a key component of the 68th World Health Assembly Global Action Plan on AMR. Laboratory-based surveillance is inherently biased and lacks local relevance due to aggregation of data. We assessed the feasibility, sensitivity, and affordability of a population-based AMR survey using lot quality assurance sampling (LQAS), which classifies a population as having a high or low prevalence of AMR based on a priori defined criteria. Three studies were carried out in Medan and Bandung, Indonesia, between April 2014 and June 2017. LQAS classifications for 15 antibiotics were compared with AMR estimates from a conventional population-based survey, with an assessment of the cost of a single LQAS classification using microcosting methodology, amon

SUBMITTER: Ginting F 

PROVIDER: S-EPMC6438814 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature