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1H, 15N, 13C resonance assignment of the human CD44 cytoplasmic tail (669-742).


ABSTRACT: CD44 is a universally and abundantly expressed single-pass type I protein that spans the cytoplasmic membrane and is considered the principal receptor for hyaluronan in the extracellular matrix. CD44 exerts a multitude of biological functions, especially in cell adhesion and migration, and its deregulation has several pathological implications, including a putative role in cancer cell dissemination. Here we report the NMR chemical shift assignment of the recombinant intrinsically disordered CD44 cytoplasmic region (669-742).

SUBMITTER: Fruhbauer B 

PROVIDER: S-EPMC6439174 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature