Efficacy of parenteral glutamine supplementation in adult hematopoietic stem cell transplantation patients.

ABSTRACT:

Background

Hematopoietic stem cell transplantation (HSCT) patients need parenteral nutrition because of nausea, vomiting, and mucositis caused by conditioning regimens. The demand for glutamine increases during the HSCT period. We evaluated the effects of glutamine-containing parenteral nutrition on the clinical outcomes of HSCT patients.

Methods

In this retrospective analysis, we reviewed HSCT patients from Seoul National University from August 2013 to July 2017. Depending on their glutamine supplementation status, 91 patients were divided into 2 groups: glutamine group (N=44) and non-glutamine group (N=47). We analyzed the rate of weight change, infection (clinically/microbiologically documented), complications (duration of mucositis and neutropenia, acute graft versus hos

SUBMITTER: Cho YK 

PROVIDER: S-EPMC6439295 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature