Intravascular B-cell lymphoma: case report of a rare cause of pulmonary arterial hypertension.

ABSTRACT:

Background

Intravascular large B-cell lymphoma (IVLBCL) is a rare disease characterized by proliferation of malignant lymphoid cells within the small vessels of various organs resulting in diffuse thrombosis. It most commonly affects the central nervous system and the skin, but if it involves the pulmonary arteries it can cause acute severe pulmonary hypertension (PH) and right heart failure. Early diagnosis is essential as the clinical course is extremely aggressive. In this report, we present a case of rapidly progressive PH and subsequent right ventricular (RV) failure secondary to IVLBCL. We review the important differential diagnoses and diagnostic evaluation needed to make a correct and early diagnosis.

Case summary

A 53-year-old, previously healthy man developed 2 mon

SUBMITTER: Share M 

PROVIDER: S-EPMC6439388 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature