A case report: mechanical mitral valve thrombosis in pregnancy.

ABSTRACT:

Background

Pregnancy in women with mechanical valves has a high risk of both valve thrombosis and bleeding as well as adverse effects on the foetus. There is limited data on achieving optimal anticoagulation in pregnancy and management of valve thrombosis, to achieve a successful foetal outcome, while prioritizing the mother's health. While warfarin may carry a lower risk of valve thrombosis, warfarin is teratogenic in the first trimester and is associated with increased foetal loss throughout the pregnancy. Heparin does not cross the placenta but is associated with increased maternal morbidity and mortality.

Case summary

We describe the case of a pregnant patient with thrombosis of a mechanical mitral valve presenting with an embolic stroke at 22 weeks of pregnancy. The str

SUBMITTER: Rozestraten FFJ 

PROVIDER: S-EPMC6439395 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature