Cognitive tasks and human ambulatory electrocorticography using the RNS System.

ABSTRACT:

Background

Electrocorticography studies are typically conducted in patients undergoing video EEG monitoring, but these studies are subject to confounds such as the effects of pain, recent anesthesia, analgesics, drug changes, antibiotics, and implant effects.

New method

Techniques were developed to obtain electrocorticographic (ECoG) data from freely moving subjects performing navigational tasks using the RNS^® System (NeuroPace, Inc., Mountain View, CA), a brain-responsive neurostimulation medical device used to treat focal onset epilepsy, and to align data from the RNS System with cognitive task events with high precision. These subjects had not had recent surgery, and were therefore not confounded by the perioperative variables that affect video EEG studies.

SUBMITTER: Meisenhelter S 

PROVIDER: S-EPMC6439470 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature