Genetic, Clinical, and Environmental Factors Associated With Persistent Atopic Dermatitis in Childhood.

ABSTRACT:

Importance

Knowledge about factors associated with persistence of atopic dermatitis (AD) during childhood is sparse.

Objective

To explore heritable, environmental, and clinical factors associated with persistent AD based on 13 years' follow-up of an at-risk birth cohort.

Design, setting, and participants

In the Copenhagen Prospective Study on Asthma in Childhood 2000 (COPSAC2000) clinical birth cohort study, 411 children born to mothers with asthma were followed up until the age of 13 years at a clinical research unit in Copenhagen, Denmark, from August 1998 to June 2015. Atopic dermatitis was diagnosed prospectively during close clinical follow-up according to the criteria of Hanifin and Rajka. Data were gathered on parental history, social circumstances, and environ

SUBMITTER: Thorsteinsdottir S 

PROVIDER: S-EPMC6439574 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature