Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients.

ABSTRACT:

Importance

Squamous cell carcinoma (SCC) is the most frequent malignant neoplasm found in solid organ transplant recipients and is associated with a more aggressive disease course and higher risk of metastasis and death than in the general population.

Objectives

To report the clinicopathologic features of and identify factors associated with aggressive SCC in solid organ transplant recipients.

Methods

This retrospective multicentric case series included 51 patients who underwent solid organ transplantation and were found to have aggressive SCC, defined by nodal or distant metastasis or death by local progression of primary SCC. Standard questionnaires were completed by the researchers between July 18, 2005, and January 1, 2015. Data were analyzed between February 22,

SUBMITTER: Lanz J 

PROVIDER: S-EPMC6439577 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature