Incidence, Characteristics, and Outcomes of Myocardial Infarction in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial.

ABSTRACT:

Importance

Patients with peripheral artery disease (PAD) are at high risk for myocardial infarction (MI).

Objective

To characterize the incidence and types of MI in a PAD population, identify factors associated with MI, and determine the association of MI with cardiovascular mortality and acute limb ischemia.

Design, setting, and participants

The Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease (EUCLID) was a double-blind randomized clinical trial conducted at 811 sites in 28 countries that randomized 13 885 patients with symptomatic PAD to monotherapy with ticagrelor or clopidogrel. Participants had an ankle-brachial index (ABI) of 0.80 or less or previous lower extremity revascularization. Median follow-

SUBMITTER: Olivier CB 

PROVIDER: S-EPMC6439683 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature