Association of Electronic Cigarette Vaping and Cigarette Smoking With Decreased Random Flap Viability in Rats.

ABSTRACT:

Importance

Smoking is a known risk to wound healing, but whether electronic cigarettes present the same risk remains unknown.

Objective

To evaluate the rate of flap necrosis in the e-cigarette vapor-exposed group and the unexposed control and to detect a difference in the rate of flap necrosis between the traditional cigarette smoke-exposed group and the unexposed control.

Design, setting, and participants

From March 10, 2018, to May 4, 2018, a cohort study was conducted on 45 male Sprague-Dawley rats at Boston University School of Medicine. Each rat weighed approximately 100 g at the beginning of the study and was randomized to 1 of 3 groups: negative control (n = 15), experimental (exposed to e-cigarette vapor; n = 15), and positive control (exposed to traditional c

SUBMITTER: Troiano C 

PROVIDER: S-EPMC6439741 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature