Association of Severe Hydrocephalus With Congenital Zika Syndrome.

ABSTRACT:

Importance

Hydrocephalus is a treatable but potentially fatal complication that has not been previously described in congenital Zika syndrome (CZS).

Objective

To describe the clinical features and imaging findings in 24 patients with congenital Zika syndrome (CZS) who developed hydrocephalus.

Design, setting, and participants

This case series included patients with hydrocephalus who were born in October and November 2015 and followed up until mid-2017 in the 2 largest national referral centers for CZS in Brazil. The participants included consecutively enrolled children with a clinical and laboratorial diagnosis of CZS who developed clinical and/or image findings suggestive of hydrocephalus and who were confirmed to experience increased intracranial hypertension during

SUBMITTER: van der Linden V 

PROVIDER: S-EPMC6439957 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature