Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths.

ABSTRACT:

Importance

Children and youths who are prescribed antipsychotic medications have multiple, potentially fatal, dose-related cardiovascular, metabolic, and other adverse events, but whether or not these medications are associated with an increased risk of death is unknown.

Objective

To compare the risk of unexpected death among children and youths who are beginning treatment with antipsychotic or control medications.

Design, setting, and participants

This retrospective cohort study was conducted from 1999 through 2014 and included Medicaid enrollees aged 5 to 24 years in Tennessee who had no diagnosis of severe somatic illness, schizophrenia or related psychoses, or Tourette syndrome or chronic tic disorder. Data analysis was performed from January 1, 2017, to August 15

SUBMITTER: Ray WA 

PROVIDER: S-EPMC6440238 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature