Association of Long-term Ambient Black Carbon Exposure and Oxidative Stress Allelic Variants With Intraocular Pressure in Older Men.

ABSTRACT:

Importance

Elevated intraocular pressure is a major risk factor for glaucoma, a leading cause of irreversible blindness worldwide. Environmental air pollution has been suggested as a potential contributor to elevated intraocular pressure; however, no studies have demonstrated such an association to date.

Objective

To investigate the association of long-term ambient black carbon exposure with intraocular pressure in community-dwelling older adults.

Design, setting, and participants

This population-based analysis, conducted from October 18, 2017, through March 22, 2018, used data from the all-male, New England-based Normative Aging Study of the US Department of Veterans Affairs. The analysis included 419 older men with a total of 911 follow-up study visits between Janua

SUBMITTER: Nwanaji-Enwerem JC 

PROVIDER: S-EPMC6440251 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature