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The Hypervirulent Strain of Clostridium Difficile: NAP1/B1/027 - A Brief Overview.


ABSTRACT: Clostridium difficile is a gram-positive bacterium notorious for causing epidemic diarrhea globally with a significant health burden. The pathogen is clinically challenging with increasing antibiotic resistance and recurrence rate. We provide here an in-depth review of one particular strain/ribotype 027, commonly known as NAP1/B1/027 or North American pulsed-field gel electrophoresis type 1, restriction endonuclease analysis type B1, polymerase chain reaction ribotype 027, which has shown a much higher recurrence rate than other strains.

SUBMITTER: Fatima R 

PROVIDER: S-EPMC6440555 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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The Hypervirulent Strain of Clostridium Difficile: NAP1/B1/027 - A Brief Overview.

Fatima Rawish R   Aziz Muhammad M  

Cureus 20190129 1


Clostridium difficile is a gram-positive bacterium notorious for causing epidemic diarrhea globally with a significant health burden. The pathogen is clinically challenging with increasing antibiotic resistance and recurrence rate. We provide here an in-depth review of one particular strain/ribotype 027, commonly known as NAP1/B1/027 or North American pulsed-field gel electrophoresis type 1, restriction endonuclease analysis type B1, polymerase chain reaction ribotype 027, which has shown a much  ...[more]

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