Assessment of Late Mortality Risk After Allogeneic Blood or Marrow Transplantation Performed in Childhood.

ABSTRACT:

Importance

Allogeneic blood or marrow transplantation (BMT) is a curative option for malignant and nonmalignant diseases of childhood. However, little is known about trends in cause-specific late mortality in this population during the past 3 decades.

Objectives

To examine cause-specific late mortality among individuals who have lived 2 years or more after allogeneic BMT performed in childhood and whether rates of late mortality have changed over time.

Design, setting, and participants

A retrospective cohort study was conducted of individuals who lived 2 years or more after undergoing allogeneic BMT performed in childhood between January 1, 1974, and December 31, 2010. The end of follow-up was December 31, 2016.

Exposure

Allogeneic BMT performed in childhood.

SUBMITTER: Holmqvist AS 

PROVIDER: S-EPMC6440718 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature