The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation.

ABSTRACT:

Background

Placental efficiency (PE) describes the relationship between placental and fetal weights (fetal wt/placental wt). Within litters, PE can vary drastically, resulting in similarly sized pigs associated with differently sized placentas, up to a 25% weight difference. However, the mechanisms enabling the smaller placenta to grow a comparable littermate are unknown. To elucidate potential mechanisms, morphological measurements and gene expression profiles in placental and associated endometrial tissues of high PE and low PE feto-placental units were compared. Tissue samples were obtained from eight maternal line gilts during gestational day 95 ovario-hysterectomies. RNA was extracted from tissues of feto-placental units with the highest and lowest PE in each litter and sequen

SUBMITTER: Krombeen SK 

PROVIDER: S-EPMC6441153 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature