Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia.

ABSTRACT: Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM.

SUBMITTER: Bai X 

PROVIDER: S-EPMC6441353 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature