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Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia.

ABSTRACT: Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM.

SUBMITTER: Bai X

PROVIDER: S-EPMC6441353 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia.

Bai Xinyue X Yang Xianjie X Cheng Yun Y Chen Ling L

Stem cell research 20181214

Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM. ...[more]

PMID: 30611020

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