Effect of alcohol ingestion on plasma glucose kinetics after Roux-en-Y gastric bypass surgery.

ABSTRACT: BACKGROUND:Roux-en-Y gastric bypass surgery (RYGB) increases the rate of alcohol absorption so that peak blood alcohol concentration is 2-fold higher after surgery compared with concentrations reached after consuming the same amount presurgery. Because high doses of alcohol can lead to hypoglycemia, patients may be at increased risk of developing hypoglycemia after alcohol ingestion. OBJECTIVES:We conducted 2 studies to test the hypothesis that the consumption of approximately 2 standard drinks of alcohol would decrease glycemia more after RYGB than before surgery. SETTING:Single-center prospective randomized trial. METHODS:We evaluated plasma glucose concentrations and glucose kinetics (assessed by infusing a stable isotopically labelled glucose tracer) after ingestion of a nonalcoholic d

SUBMITTER: Acevedo MB 

PROVIDER: S-EPMC6441624 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature