Ambient temperature and preterm birth: A retrospective study of 32 million US singleton births.

ABSTRACT:

Background

Days of extreme temperature may be associated with transiently higher risk of preterm birth, but prior studies have been limited and results have been heterogeneous.

Objectives

To evaluate the association between days of extreme heat and cold and risk of preterm birth among ~32 million live singleton births between 1989 and 2002 across 403 counties in the contiguous United States (US).

Methods

We used a distributed lag nonlinear model to estimate the association between population-weighted daily mean temperature and risk of preterm birth in each county and then pooled results across geographic regions and climate zones. We defined extreme heat and cold as the 95th and 5th percentile of the county-specific temperatures, respectively.

Results

Preterm b

SUBMITTER: Sun S 

PROVIDER: S-EPMC6441631 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature