The Association Between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia.

ABSTRACT:

Background

Association between high adiposity and the clinical progression of dementia remains puzzling.

Objective

To separately examine the association between body mass index (BMI) and cognitive, functional, and behavioral declines before, at, and after diagnosis of dementia, and further stratified by age groups, and sex.

Methods

A total of 1,141 individuals with incident dementia were identified from the Uniform Data Set of the National Alzheimer's Coordinating Center. Cognitive function was evaluated by Mini-Mental State Exam, functional abilities were assessed using Functional Activities Questionnaire, and behavioral symptoms were captured by Neuropsychiatric Inventory Questionnaire at each follow-up visit. We used separate linear-mixed effects models to examine

SUBMITTER: Michaud TL 

PROVIDER: S-EPMC6441968 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature