Physiologic response to pre-arrest bolus dilute epinephrine in the pediatric intensive care unit.

ABSTRACT:

Aim

To quantify the physiologic effects of pre-arrest bolus dilute epinephrine in the pediatric intensive care unit.

Methods

Patients <18 years old and ≥37 weeks gestation who received an intravenous bolus of dilute epinephrine (10 mcg/mL) in the pediatric intensive care units at our institution from January 2011 to March 2017 were retrospectively identified. Patients were excluded if doses exceeded 20 mcg/kg, or under the following circumstances: orders limiting resuscitation, extracorporeal membrane oxygenation, active chest compressions, simultaneous administration of other blood pressure-altering interventions or documented normotension prior to epinephrine. The primary outcome was change in systolic blood pressure within 5 min of epinephrine. Patients were categorized a

SUBMITTER: Ross CE 

PROVIDER: S-EPMC6441975 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature