Chemical composition, anti-toxoplasma, cytotoxicity, antioxidant, and anti-inflammatory potentials of Cola gigantea seed oil.

ABSTRACT:

Context

Cola gigantea A. Chev. (Sterculiaceae) is an important medicinal tropical flora.

Objective

The seed oil of C. gigantea, an underutilized tropical plant was investigated for its antioxidant, anti-inflammatory, anti-Toxoplasma, and cytotoxicity activities as well as the chemical composition.

Materials and methods

The physicochemical parameters of the seed oil obtained via Soxhlet extraction was determined while the fatty acid and non-fatty acid component were analyzed by gas chromatography-mass spectrometry. The antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays (10-50 µg/mL) while the anti-inflammatory property was determined through Cell Membrane Stabilization

SUBMITTER: Atolani O 

PROVIDER: S-EPMC6442224 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature