Dataset Information

Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients.

ABSTRACT:

Context

Amaranth and canola oils have been used traditionally. Amaranth has been identified as being of interest because of its outstanding nutritive value. Amaranth oil is a rich source of highly unsaturated fats and so could be a valuable dietary alternative for individuals affected with obesity. Reactive oxygen species (ROS) are postulated to be involved in systemic inflammation and oxidative stress. Activated polymorphonuclear neutrophils (PMNs) generate high amounts of reactive oxygen species.

Objective

Our study investigates the impact of amaranth and canola oils supplementation on oxidative metabolism in patients with obesity. We hypothesized that, due to its lipid-lowering and antioxidant properties, amaranth and canola oil would protect against oxidative stress.

Materials and methods

We tested 19 obese patients [body mass index (BMI) = 41.1 ± 7.8 kg/m², (mean ± SD)]. The protocol consisted of two stages: a run-in phase of 2 weeks and an experimental stage - canola or amaranth oil supplementation (20 mL/d) with calorie restriction diet for 3 weeks. The neutrophil oxidative burst was expressed by fluorescence intensity (IF).

Results

The oxidative burst had increased significantly at the end of treatment in both groups IF: (21.4 ± 11.15 vs. 35.9 ± 20.3; mean ± SD) p < 0.05. The levels of IF were significantly higher in neutrophils of patients who received canola oil (41.05 ± 25.3) compared to those who received amaranth oil (28.4 ± 11.8) p < 0.05.

Conclusions

Canola oil exerts possible effects on oxidative burst activity in neutrophils in vivo conditions.

SUBMITTER: Kanikowska D

PROVIDER: S-EPMC6442228 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Publications

Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients.

Kanikowska Dominika D Kanikowska Alina A Rutkowski Rafał R Włochal Małgorzata M Orzechowska Zofia Z Juchacz Aldona A Zawada Agnieszka A Grzymisławski Marian M Roszak Magdalena M Sato Maki M Bręborowicz Andrzej A Witowski Janusz J

Pharmaceutical biology 20191201 1

<h4>Context</h4>Amaranth and canola oils have been used traditionally. Amaranth has been identified as being of interest because of its outstanding nutritive value. Amaranth oil is a rich source of highly unsaturated fats and so could be a valuable dietary alternative for individuals affected with obesity. Reactive oxygen species (ROS) are postulated to be involved in systemic inflammation and oxidative stress. Activated polymorphonuclear neutrophils (PMNs) generate high amounts of reactive oxyg ...[more]

PMID: 30905230

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Dataset Information

Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients.

Context

Objective

Materials and methods

Results

Conclusions

Publications

Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients.

Similar Datasets

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