Comparison of three lymph node staging schemes for predicting the outcome in patients with small bowel adenocarcinoma: A population-based cohort and international multicentre cohort study.

ABSTRACT:

Background

The prognostic roles of three common lymph node staging schemes, number of positive lymph nodes (pN), lymph node ratio (LNR) and log odds of positive lymph nodes (LODDS) in small bowel adenocarcinoma (SBA) are unclear. We assessed their prognostic ability in SBA.

Methods

A total of 2128 patients diagnosed with SBA between 1988 and 2010 from the Surveillance, Epidemiology, and End Results (SEER) database and 186 patients from 15 hospitals in France and China were identified. We evaluated the prognostic ability of the schemes in both continuous and stratified patterns using R², Harrell's C, and time-dependent receiver operating characteristic curve analyses.

Findings

For continuous pattern, the LODDS had a better capacity of discrimination and high

SUBMITTER: Zhou YY 

PROVIDER: S-EPMC6443578 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature