Testing Empirical Support for Evolutionary Models that Root the Tree of Life.

ABSTRACT: Trees of life (ToLs) can only be rooted with direct methods that seek optimization of character state information in ingroup taxa. This involves optimizing phylogenetic tree, model and data in an exercise of reciprocal illumination. Rooted ToLs have been built from a census of protein structural domains in proteomes using two kinds of models. Fully-reversible models use standard-ordered (additive) characters and Wagner parsimony to generate unrooted trees of proteomes that are then rooted with Weston's generality criterion. Non-reversible models directly build rooted trees with unordered characters and asymmetric stepmatrices of transformation costs that penalize gain over loss of domains. Here, we test the empirical support for the evolutionary models with character state reconstruction m

SUBMITTER: Caetano-Anolles D 

PROVIDER: S-EPMC6443624 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature