Oral glucose load and mixed meal feeding lowers testosterone levels in healthy eugonadal men.

ABSTRACT:

Purpose

Precise evaluation of serum testosterone levels is important in making an accurate diagnosis of androgen deficiency. Recent practice guidelines on male androgen deficiency recommend that testosterone be measured in the morning while fasting. Although there is ample evidence regarding morning measurement of testosterone, studies that evaluated the effect of glucose load or meals were limited by inclusion of hypogonadal or diabetic men, and measurement of testosterone was not performed using mass spectrometry.

Methods

Sixty men (23-97 years) without pre-diabetes or diabetes who had normal total testosterone (TT) levels underwent either an oral glucose tolerance test (OGTT) or a mixed meal tolerance test (MMTT) after an overnight fast. Serum samples were collected befor

SUBMITTER: Gagliano-Juca T 

PROVIDER: S-EPMC6445266 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature