Study of occupation and amyotrophic lateral sclerosis in a Danish cohort.

ABSTRACT:

Objectives

Several manuscripts have proposed associations between amyotrophic lateral sclerosis (ALS) and occupational toxicant exposures-not to mention physical activity and trauma/injury. Some have also reported associations in investigations of specific occupations. Using data from a prospective Danish cohort study, we investigated the association between employment in certain industries and ALS diagnosis.

Methods

We identified 1826 ALS cases who were 25 years old or less in 1964 and diagnosed from 1982 to 2013 from the Danish National Patient Registry then matched 100 population controls to each case based on birth year and sex. Demographic data were linked to the Danish Pension Fund to determine occupation history. Conditional logistic regression models were adjusted fo

SUBMITTER: Dickerson AS 

PROVIDER: S-EPMC6445390 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature