Impact of universal drug susceptibility testing and effective management of multidrug-resistant tuberculosis in Taiwan.

ABSTRACT:

Background

The treatment outcomes of multidrug-resistant tuberculosis (MDR-TB) patients in the 1990s in Taiwan was not satisfactory. To strengthen programmatic management of drug-resistant tuberculosis (PMDT), Taiwan MDR-TB Consortium (TMTC) was established in 2007. We assess the performance and epidemiologic impact of TMTC.

Methodology/principle findings

We analyzed the trends of proportion of TB cases with drug susceptibility testing, enrollment of MDR-TB patients into TMTC and outcomes of treatment of all MDR-TB patients in Taiwan from 2007-2016. We computed the trends of both incidence and prevalence of MDR-TB from 2007-2016. We assessed the trends of MDR-TB among both new and recurrent TB cases. The proportion of TB cases with drug susceptibility testing results increas

SUBMITTER: Lee PH 

PROVIDER: S-EPMC6445419 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature