Fetal exposure to maternal active and secondhand smoking with offspring early-life growth in the Healthy Start study.

ABSTRACT:

Background

Previous studies have modeled the association between fetal exposure to tobacco smoke and body mass index (BMI) growth trajectories, but not the timing of catch-up growth. Research on fetal exposure to maternal secondhand smoking is limited.

Objectives

To explore the associations between fetal exposure to maternal active and secondhand smoking with body composition at birth and BMI growth trajectories through age 3 years.

Methods

We followed 630 mother-child pairs enrolled in the Healthy Start cohort through age 3 years. Maternal urinary cotinine was measured at ~ 27 weeks gestation. Neonatal body composition was measured using air displacement plethysmography. Child weight and length/height were abstracted from medical records. Linear regression models exa

SUBMITTER: Moore BF 

PROVIDER: S-EPMC6445676 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature