Ontology highlight
ABSTRACT:
SUBMITTER: Miller SM
PROVIDER: S-EPMC6446555 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Miller Samara M SM Marcotulli Daniele D Shen Angela A Zweifel Larry S LS
Nature neuroscience 20190225 4
Avoidance of innate threats is often in conflict with motivations to engage in exploratory approach behavior. The neural pathways that mediate this approach-avoidance conflict are not well resolved. Here we isolated a population of dopamine D1 receptor (D1R)-expressing neurons within the posteroventral region of the medial amygdala (MeApv) in mice that are activated either during approach or during avoidance of an innate threat stimulus. Distinct subpopulations of MeApv-D1R neurons differentiall ...[more]