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Autism-Related Variation in Reciprocal Social Behavior: A Longitudinal Study.


ABSTRACT: Deficits in reciprocal social behavior are a characterizing feature of autism spectrum disorder (ASD). Autism-related variation in reciprocal social behavior (AVR) in the general population is continuously distributed and highly heritable-a function of additive genetic influences that overlap substantially with those which engender clinical autistic syndromes. This is the first long-term prospective study of the stability of AVR from childhood through early adulthood, conducted via serial ratings using the Social Responsiveness Scale, in a cohort-sequential study involving children with ASD, other psychiatric conditions, and their siblings (N = 602, ages = 2.5-29). AVR exhibits marked stability throughout childhood in individuals with and without ASD.

SUBMITTER: Wagner RE 

PROVIDER: S-EPMC6446804 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Autism-Related Variation in Reciprocal Social Behavior: A Longitudinal Study.

Wagner Rachael E RE   Zhang Yi Y   Gray Teddi T   Abbacchi Anna A   Cormier Deporres D   Todorov Alexandre A   Constantino John N JN  

Child development 20181022 2


Deficits in reciprocal social behavior are a characterizing feature of autism spectrum disorder (ASD). Autism-related variation in reciprocal social behavior (AVR) in the general population is continuously distributed and highly heritable-a function of additive genetic influences that overlap substantially with those which engender clinical autistic syndromes. This is the first long-term prospective study of the stability of AVR from childhood through early adulthood, conducted via serial rating  ...[more]

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