Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection.

ABSTRACT:

Importance

Whether low levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased risk of sepsis and poorer outcomes is unknown.

Objective

To examine the association between LDL-C levels and risk of sepsis among patients admitted to the hospital with infection.

Design, setting, and participants

Cohort study in which deidentified electronic health records were used to define a cohort of patients admitted to Vanderbilt University Medical Center, Nashville, Tennessee, with infection. Patients were white adults, had a code indicating infection from the International Classification of Diseases, Ninth Revision, Clinical Modification, and received an antibiotic within 1 day of hospital admission (N = 61 502). Data were collected from January 1, 1993,

SUBMITTER: Feng Q 

PROVIDER: S-EPMC6447031 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature