A quick guide for student-driven community genome annotation.

ABSTRACT: High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental validation over the course of many years. The majority of gene models present in biological databases today have been identified in draft genome assemblies using automated annotation pipelines that are frequently based on orthologs from distantly related model organisms and usually have minor or major errors. Manual curation is time consuming and often requires substantial expertise, but is instrumental in improving gene model structure and identification. Manual annotation may seem to be a daunting and cost-prohibitive task for small research communities but in

SUBMITTER: Hosmani PS 

PROVIDER: S-EPMC6447164 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature