Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour.

ABSTRACT: Categorically distinct basic drives (for example, for social versus feeding behaviour^1-3) can exert potent influences on each other; such interactions are likely to have important adaptive consequences (such as appropriate regulation of feeding in the context of social hierarchies) and can become maladaptive (such as in clinical settings involving anorexia). It is known that neural systems regulating natural and adaptive caloric intake, and those regulating social behaviours, involve related circuitry^4-7, but the causal circuit mechanisms of these drive adjudications are not clear. Here we investigate the causal role in behaviour of cellular-resolution experience-specific neuronal populations in the orbitofrontal cortex, a major reward-processing hub that contains div

SUBMITTER: Jennings JH 

PROVIDER: S-EPMC6447429 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature