Uncovering carbohydrate metabolism through a genotype-phenotype association study of 56 lactic acid bacteria genomes.

ABSTRACT: Owing to their unique potential to ferment carbohydrates, both homo- and heterofermentative lactic acid bacteria (LAB) are widely used in the food industry. Deciphering the genetic basis that determine the LAB fermentation type, and hence carbohydrate utilization, is paramount to optimize LAB industrial processes. Deep sequencing of 24 LAB species and comparison with 32 publicly available genome sequences provided a comparative data set including five major LAB genera for further analysis. Phylogenomic reconstruction confirmed Leuconostoc and Pediococcus species as independently emerging from the Lactobacillus genus, within one of the three phylogenetic clades identified. These clades partially grouped LABs according to their fermentation types, suggesting that some metabolic capabilities

SUBMITTER: Buron-Moles G 

PROVIDER: S-EPMC6447522 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature