Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.

ABSTRACT: A critical component in the interpretation of systems-level studies is the inference of enriched biological pathways and protein complexes contained within OMICs datasets. Successful analysis requires the integration of a broad set of current biological databases and the application of a robust analytical pipeline to produce readily interpretable results. Metascape is a web-based portal designed to provide a comprehensive gene list annotation and analysis resource for experimental biologists. In terms of design features, Metascape combines functional enrichment, interactome analysis, gene annotation, and membership search to leverage over 40 independent knowledgebases within one integrated portal. Additionally, it facilitates comparative analyses of datasets across multiple independent and

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC6447622 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature