Postprandial Amino Acid Kinetics of Milk Protein Mixtures are Affected by Composition, But Not Denaturation, in Neonatal Piglets.

ABSTRACT:

Background

Multiple studies have indicated that formula-fed infants show a different growth trajectory compared with breastfed infants. The observed growth rates are suggested to be linked to higher postprandial levels of branched chain amino acids (BCAAs) and insulin related to differences in protein quality.

Objective

We evaluated the effects of milk protein denaturation and milk protein composition on postprandial plasma and hormone concentrations.

Methods

Neonatal piglets were bolus-fed randomly, in an incomplete crossover design, 2 of 3 milk protein solutions: native whey protein isolate (NWPI), denatured whey protein isolate (DWPI), or protein base ingredient, comprising whey and casein (PBI). Postprandial plasma amino acids (AAs), insulin, glucagon-like peptide

SUBMITTER: Welch-Jernigan RJ 

PROVIDER: S-EPMC6447734 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature