Sensitivity of dose-volume indices to computation settings in high-dose-rate prostate brachytherapy treatment plan evaluation.

ABSTRACT:

Purpose

To investigate the variation in computed dose-volume (DV) indices for high-dose-rate (HDR) prostate brachytherapy that can result from typical differences in computation settings in treatment planning systems (TPSs).

Methods

Five factors were taken into account: number of dose-calculation points, radioactive source description, interpolation between delineated contours, intersections between delineated organ contours, and organ shape at the top and bottom contour using either full or partial slice thickness. Using in-house developed software, the DV indices of the treatment plans of 26 patients were calculated with different settings, and compared to a baseline setting that closely followed the default settings of the TPS used in our medical center. Studied organs we

SUBMITTER: van der Meer MC 

PROVIDER: S-EPMC6448172 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature