Effect of Age on Opioid Prescribing, Overdose, and Mortality in Massachusetts, 2011 to 2015.

ABSTRACT:

Objectives

To examine the effect of age on the likelihood of PIP of opioids and the effect of PIP on adverse outcomes.

Design

Retrospective cohort study.

Setting

Data from multiple state agencies in Massachusetts from 2011 to 2015.

Participants

Adult Massachusetts residents (N=3,078,163) who received at least one prescription opioid during the study period; approximately half (1,589,365) aged 50 and older.

Measurements

We measured exposure to 5 types of PIP: high-dose opioids, coprescription with benzodiazepines, multiple opioid prescribers, multiple opioid pharmacies, and continuous opioid therapy without a pain diagnosis. We examined 3 adverse outcomes: nonfatal opioid overdose, fatal opioid overdose, and all-cause mortality.

Results

The rate of

SUBMITTER: Rose AJ 

PROVIDER: S-EPMC6448572 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature