Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease.

ABSTRACT:

Aims/hypothesis

Sleep duration is a risk factor for incident diabetes mellitus and CHD. The primary aim of the present study was to investigate, in sex-specific analyses, the role of incident diabetes as the possible biological mechanism for the reported association between short/long sleep duration and incident CHD. Considering that diabetes is a major risk factor for CHD, we hypothesised that any association with sleep duration would not hold for cases of incident CHD occurring before incident diabetes ('non-diabetes CHD') but would hold true for cases of incident CHD following incident diabetes ('diabetes-CHD').

Methods

A total of 6966 men and 9378 women aged 45-73 years from the Malmö Diet Cancer Study, a population-based, prospective cohort, who had answered questions o

SUBMITTER: Svensson AK 

PROVIDER: S-EPMC6448951 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature