Incidental intracranial meningiomas: a systematic review and meta-analysis of prognostic factors and outcomes.

ABSTRACT:

Background

Incidental discovery accounts for 30% of newly-diagnosed intracranial meningiomas. There is no consensus on their optimal management. This review aimed to evaluate the outcomes of different management strategies for these tumors.

Methods

Using established systematic review methods, six databases were scanned up to September 2017. Pooled event proportions were estimated using a random effects model. Meta-regression of prognostic factors was performed using individual patient data.

Results

Twenty studies (2130 patients) were included. Initial management strategies at diagnosis were: surgery (27.3%), stereotactic radiosurgery (22.0%) and active monitoring (50.7%) with a weighted mean follow-up of 49.5 months (SD = 29.3). The definition of meningioma growth and

SUBMITTER: Islim AI 

PROVIDER: S-EPMC6449307 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature