A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections.

ABSTRACT:

Importance

In young febrile infants, serious bacterial infections (SBIs), including urinary tract infections, bacteremia, and meningitis, may lead to dangerous complications. However, lumbar punctures and hospitalizations involve risks and costs. Clinical prediction rules using biomarkers beyond the white blood cell count (WBC) may accurately identify febrile infants at low risk for SBIs.

Objective

To derive and validate a prediction rule to identify febrile infants 60 days and younger at low risk for SBIs.

Design, setting, and participants

Prospective, observational study between March 2011 and May 2013 at 26 emergency departments. Convenience sample of previously healthy febrile infants 60 days and younger who were evaluated for SBIs. Data were analyzed between Apri

SUBMITTER: Kuppermann N 

PROVIDER: S-EPMC6450281 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature