Prediction of incident vertebral fracture using CT-based finite element analysis.

ABSTRACT: Prior studies show vertebral strength from computed tomography-based finite element analysis may be associated with vertebral fracture risk. We found vertebral strength had a strong association with new vertebral fractures, suggesting that vertebral strength measures identify those at risk for vertebral fracture and may be a useful clinical tool.

Introduction

We aimed to determine the association between vertebral strength by quantitative computed tomography (CT)-based finite element analysis (FEA) and incident vertebral fracture (VF). In addition, we examined sensitivity and specificity of previously proposed diagnostic thresholds for fragile bone strength and low BMD in predicting VF.

Methods

In a case-control study, 26 incident VF cases (13 men, 13 women) and 62 age- and s

SUBMITTER: Allaire BT 

PROVIDER: S-EPMC6450770 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature