Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation.

ABSTRACT: Adolescent binge drinking has been associated with higher risks for the development of many health problems throughout the lifespan. Adolescents undergo multiple changes that involve the co-development processes of brain, personality and behavior; therefore, certain behavior, such as alcohol consumption, can have disruptive effects on both brain development and personality maturation. However, these effects remain unclear due to the scarcity of longitudinal studies. In the current study, we used multivariate approaches to explore discriminative features in brain functional architecture, personality traits, and genetic variants in 19-year-old individuals (n = 212). Taking advantage of a longitudinal design, we selected features that were more drastically altered in drinkers with an earlier

SUBMITTER: Ruan H 

PROVIDER: S-EPMC6451196 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature