Does pregnancy complication history improve cardiovascular disease risk prediction? Findings from the HUNT study in Norway.

ABSTRACT:

Aim

To evaluate whether history of pregnancy complications [pre-eclampsia, gestational hypertension, preterm delivery, or small for gestational age (SGA)] improves risk prediction for cardiovascular disease (CVD).

Methods and results

This population-based, prospective cohort study linked data from the HUNT Study, Medical Birth Registry of Norway, validated hospital records, and Norwegian Cause of Death Registry. Using an established CVD risk prediction model (NORRISK 2), we predicted 10-year risk of CVD (non-fatal myocardial infarction, fatal coronary heart disease, and non-fatal or fatal stroke) based on established risk factors (age, systolic blood pressure, total and HDL-cholesterol, smoking, anti-hypertensives, and family history of myocardial infarction). We evaluated w

SUBMITTER: Markovitz AR 

PROVIDER: S-EPMC6451770 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature